Survivors of severe coronavirus disease (COVID-19), particularly those who were hospitalized, are likely to suffer long-term effects. In fact, researchers suspect that survivors of severe COVID-19 infection who required mechanical ventilation might never fully recover. Ventilator use is associated with severe muscle atrophy and weakness, which significantly impact survival and quality of life.
In addition, some COVID-19 patients who have been hospitalized have experienced neurological symptoms, including severe fatigue and altered consciousness. Delirium has been observed in many patients as well, possibly as a side effect of medication. Delirium and lingering psychological issues, including depression and anxiety, can prolong and complicate recovery. Following the outbreak of severe acute respiratory syndrome (SARS) in 2003, which was also caused by a type of coronavirus, more than half of survivors were still dealing with psychological stress one year later.
Whether infection with SARS-CoV-2, the coronavirus that causes COVID-19, confers life-long immunity remains unknown. If the virus does not mutate, then anyone who carries antibodies against it is likely to be immune. However, many highly infectious viruses mutate, and they do so quickly. If SARS-CoV-2 mutates, it could reinfect survivors.